Basic Information
VIS ID
TVIS44019499
Fusion event
HTLV-1-SAP30L-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q33.2
Reference genome
GRCh37/hg19
Start
153770630/154391070 (Hg38)
End
153770630/154391070 (Hg38)
Orient
+
Location type
ncRNA_exonic
Target gene
SAP30L-AS1
Nearest miRNA
hsa-mir-10397/Upstream/43823; hsa-mir-103a-1/Downstream/204942;
Nearest TSS
ENST00000502646/Upstream/14753; ENST00000519235/Downstream/11720;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/200092, chr5-CpG: 33/Downstream/14011
Upstream sequence
GAGGAAATGAGACAGTGTAATGAGGAGGCTCCTGAGGTCCGGAAGGGAGACTTTTCTCCCTGGGCTTTCTCTCTCCTGGCTTGGAAAAGGAGAGTTTCTG
Downstream sequence
GAGCCAGCAACAGCCCATCTGCCAGTGCACTGTCTCCCAGGACCCTGTGGAAAGACTGCCTGCAGGGCTGAGGGGAACAGGTGAGCCCATTCATCCCTGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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