Basic Information
VIS ID
TVIS44019504
Fusion event
HTLV-1-SOX30 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q33.3
Reference genome
GRCh37/hg19
Start
157095462/157668454 (Hg38)
End
157095462/157668454 (Hg38)
Orient
-
Location type
Intronic
Target gene
SOX30
miRNAs that regulate target gene
hsa-mir-3119 ; hsa-mir-645
Nearest miRNA
hsa-mir-10397/Upstream/2838914; hsa-mir-103a-1/Downstream/2805948;
Nearest TSS
ENST00000502646/Upstream/16034; ENST00000409999/Downstream/3026;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/15898, chr5-CpG: 81/Downstream/2801
Upstream sequence
AGGATCCTGCCAAAGGGTTAGCCAGCTGGAATCAGAGGGGTAACTTGTCAGGGAGCAGGGGGAGGTAGGTAGCTGCTGAAGTTGCTGCTAAGAGTGATCC
Downstream sequence
CAAAGTTCTGACATATCTGTCTcatccatccatccattcatccattcactcaccaatccatccatccatccactcatccatccatccactcatccatcca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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