Basic Information
VIS ID
TVIS44019510
Fusion event
HTLV-1-LOC105377703 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q34
Reference genome
GRCh37/hg19
Start
163835278/164408272 (Hg38)
End
163835278/164408272 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105377703
Nearest miRNA
hsa-mir-10397/Upstream/3922822; hsa-mir-103a-1/Downstream/3757573;
Nearest TSS
ENST00000502646/Upstream/54119; ENST00000519901/Downstream/59018;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/902332, chr5-CpG: 17/Downstream/2570207
Upstream sequence
GAAAGAACTAAATAAACAGATCTAATATTGTAAAATAGAATTTGCAAGAAAGTACATATTTTGCTGAACTATGCTATAGATAAGTTCTTTACTTGTCTTT
Downstream sequence
CCCAAAATCTTTTCGTTATTTTGAAGatataattaaaataattataaaGTAATAACAGCACGTATTATGCACATCATATATACCACAAATAatgaaattg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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