Basic Information
VIS ID
TVIS44019519
Fusion event
HTLV-1-chr5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
GRCh37/hg19
Start
1745709/1745594 (Hg38)
End
1745709/1745594 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-4277/Upstream/36726; hsa-mir-10397/Downstream/5082259;
Nearest TSS
ENST00000502646/Upstream/20445; ENST00000510329/Downstream/54156;
Nearest CpG islands
chr5-CpG: 23/Target, None/Upstream, None/Downstream
Nearby gene
MIR4277(-36726) ;
Upstream sequence
GGTCGGGTAGCATCCATCCTGGCTGGCCGCACCCGCATTTCCGTGTCGCATGATCCATCCGGTGCCTCTGCAGACAGCAGGCACTAGGACAGATGGGCTG
Downstream sequence
GAGCTGGCATATCGTGCGGATAAACTGTTTATCACTCCATTGACGCCGCTCCATCTCCCCGCAGCTGACCCCACGCTCACTAATGCCTAGATAGTGGGCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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