Basic Information
VIS ID
TVIS44019536
Fusion event
HTLV-1-C5orf17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p14.2
Reference genome
GRCh37/hg19
Start
24071337/24071228 (Hg38)
End
24071337/24071228 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA5E
Target gene
C5orf17
Nearest miRNA
hsa-mir-10397/Upstream/6915236; hsa-mir-103a-1/Downstream/7864874;
Nearest TSS
ENST00000502646/Upstream/119664; ENST00000510391/Downstream/282215;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/2611485, chr5-CpG: 68/Downstream/1119166
Upstream sequence
AGTGCATCCCTTGTGCCTTTAGTTAACAAAACATCCATCCTGTGGGGCAGCAAGACTGCTAAATAGACATCTGCACAATGTTGGAATCCAGGCTTTACTC
Downstream sequence
AGGATGGCTGCTCTGGGCACTACTTTCATCTAAGCAAATGCAATAACTTTAGGGAATAACAGTGAATTTTTTCCCTAAACAGTTATCACAATGCCACTGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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