Basic Information
VIS ID
TVIS44019542
Fusion event
HTLV-1-C1QTNF3-AMACR integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
34006013/34005908 (Hg38)
End
34006013/34005908 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA5A
Target gene
C1QTNF3-AMACR
Nearest miRNA
hsa-mir-10397/Upstream/1611433; hsa-mir-103a-1/Downstream/2141984;
Nearest TSS
ENST00000502646/Upstream/21178; ENST00000607051/Downstream/2120;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/67704, chr5-CpG: 60/Downstream/1783
Upstream sequence
GACTGGCCAAATCCACTCAGCCTGGCATAAATAAGCCTTGGATTTTCCCGCTGCAGAATCTCTGGGCCCAGCTGGAGTTTCTCCATGACACCTTAAGAGA
Downstream sequence
AAAGTAACGATCTTCTTAAGAGAGTATGAATTGAGGATGGAGATAATCCCTTCTCTGAGACAAACATAAAATAGCACCATTGCAAGTAATATTAATAACA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate