Basic Information
VIS ID
TVIS44019548
Fusion event
HTLV-1-LOC105374724 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
35854133/35854031 (Hg38)
End
35854133/35854031 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA5A
Target gene
LOC105374724
Nearest miRNA
hsa-mir-10397/Upstream/3459556; hsa-mir-103a-1/Downstream/293861;
Nearest TSS
ENST00000502646/Upstream/1308; ENST00000515665/Downstream/2264;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/235794, chr5-CpG: 85/Downstream/297364
Nearby gene
IL7R(+2844) ;
Upstream sequence
gtcttgaactcctgagctcaagtgatctgcccacctcagcttcccaaggtgttgggattacaggcatgagccactgcacccagcTGGCTTTCCTTTTTAA
Downstream sequence
TGATTCACTACATCATACAAACTCATCAAACTGAAGGAAGACAAAGTACAAAAGAGAGACGAGAAAATGTAGCCATGAAAGGAAGTGATGGGTGAAGAGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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