Basic Information
VIS ID
TVIS44019556
Fusion event
HTLV-1-GHR integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p12
Reference genome
GRCh37/hg19
Start
42553500/42553398 (Hg38)
End
42553500/42553398 (Hg38)
Orient
-
Location type
Intronic
Target gene
GHR
Nearest miRNA
hsa-mir-10397/Upstream/3995837; hsa-mir-103a-1/Downstream/11398106;
Nearest TSS
ENST00000502646/Upstream/3318; ENST00000513625/Downstream/12458;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/128453, chr5-CpG: 47/Downstream/370714
Upstream sequence
tgttttcatgaactgagttccttgtcattgttggaccatgttccccatttccttgctggctgtcagctgggagccagtttttgctcctagaggctatctg
Downstream sequence
cattgcatctcatggtttctgtgtgcccccttccagcaacaagattctatgtacccccttccagcaacaatattctatgtaccctcttccagcaacagaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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