Basic Information
VIS ID
TVIS44019567
Fusion event
HTLV-1-LINC01020 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p15.32
Reference genome
GRCh37/hg19
Start
5057730/5057617 (Hg38)
End
5057730/5057617 (Hg38)
Orient
-
Location type
ncRNA_exonic
Target gene
LINC01020
Nearest miRNA
hsa-mir-4277/Upstream/3348749; hsa-mir-10397/Downstream/1770236;
Nearest TSS
ENST00000502646/Upstream/8120; ENST00000514474/Downstream/114;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/191100, chr5-CpG: 148/Downstream/81711
Upstream sequence
AGTACACAGGCAAACGTAACTCCCTCTCTTATGTGTCCTCCCAGAATTTTACTCAGTCACGTTGCTCACTGCTGCGCACTCCTGCAGACGCATCCCAGTG
Downstream sequence
GACTCTGCGCTGCATCCCCAGAGTACAGCGAGTTTCCCGCCTCCCGTTAGAGATCCAACACATATTTTTTTTGAAAGAAGAAACTGATGGAAGACAGGAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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