Basic Information
VIS ID
TVIS44019592
Fusion event
HTLV-1-LOC105379012 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
67787019/68491192 (Hg38)
End
67787019/68491192 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105379012
Nearest miRNA
hsa-mir-10397/Upstream/8787489; hsa-mir-103a-1/Downstream/3678275;
Nearest TSS
ENST00000502646/Upstream/56711; ENST00000515504/Downstream/32686;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/202569, chr5-CpG: 62/Downstream/602658
Nearby gene
PIK3R1(+189370) ;
Upstream sequence
ACAAAAATGACAGTTTGGGGCTAGATTTGGGATGAAACTATCAAACCAAATAGTGATGACTGGCGAATAATGTTTTTGACCCTGAATTATAGTTGAGGag
Downstream sequence
cagtagtcatggtataagcataggctaaggataagattgcttgctgtttgaatccctatcctgcttcttgattgggtgatactggatatcaaactgtgtg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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