Basic Information
VIS ID
TVIS44019620
Fusion event
HTLV-1-NR2F1-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q15
Reference genome
GRCh37/hg19
Start
92805399/93469693 (Hg38)
End
92805399/93469693 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA5B ; FRA5D
Target gene
NR2F1-AS1
Nearest miRNA
hsa-mir-10397/Upstream/3452973; hsa-mir-103a-1/Downstream/151003;
Nearest TSS
ENST00000502646/Upstream/30956; ENST00000512697/Downstream/101100;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/2088580, chr5-CpG: 183/Downstream/100840
Upstream sequence
tttcttaggctagaaaccagattatttatcttccacaacagcttgcaccatgccttccttgcacacagtaaatactcaagaaatacatgttgaatcaata
Downstream sequence
gatACTTGAACCTCTATCTGATGCATAAATCTCCTCTAGATTTTTCCCTATTCCCTACATCCACACTCCCTGTCAGTTATTGTGGATATAGCTAGCACAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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