Basic Information
VIS ID
TVIS44019633
Fusion event
HTLV-1-KRT8P32 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q15
Reference genome
GRCh37/hg19
Start
97729155/98393451 (Hg38)
End
97729155/98393451 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA5F
Target gene
KRT8P32
Nearest miRNA
hsa-mir-10397/Upstream/2314239; hsa-mir-103a-1/Downstream/2423031;
Nearest TSS
ENST00000502646/Upstream/232258; ENST00000505265/Downstream/375199;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/1209510, chr5-CpG: 135/Downstream/375423
Nearby gene
RGMB(+375844) ;
Upstream sequence
CGCTGGCCCCACCATAGCCTCCACCCAGACCACCCAGGAAGCTGCTGCTGCTGCCCACTCAGGAGAAGCTCAAGGAGCTGATGCGGGCACTGGGCCCACT
Downstream sequence
TGTGTAGGAACAGCTGCTGAAGTCCTGGGAGCCAGAGGTGGACACCTTGTAGGACTTCTGGGTCACCCTGATGGACAAGGTGGAAGCAGGAGTGGAGGCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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