Basic Information
VIS ID
TVIS44019652
Fusion event
HTLV-1-PKIB integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q22.31
Reference genome
GRCh37/hg19
Start
122919716/122598571 (Hg38)
End
122919716/122598571 (Hg38)
Orient
-
Location type
Intronic
Target gene
PKIB
Nearest miRNA
hsa-mir-10398/Upstream/2583314; hsa-mir-1202/Downstream/3886060;
Nearest TSS
ENST00000381078/Upstream/116483; ENST00000368446/Downstream/11661;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/126625, chr6-CpG: 50/Downstream/11437
Upstream sequence
tgtatttaaattttgtagttgagtgactgcggttcccaccattagatctgacatacagagaagaacaattacagggctcttcaaagatgcaggtgctgcc
Downstream sequence
ctcacaaatttattttgcaagagattggtgaagggtatatcttctgtctgaaccctcccagctgggatgagtaggtctaaagtgactaatccactccacc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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