VISDB Viral Integration Site DataBase

VIS ID

TVIS44019673

Fusion event

HTLV-1-QKI integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr6

Cytoband

q26

Reference genome

Start

End

163913906/163492874 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-214-3p ; hsa-mir-124-3p ; hsa-mir-425-5p ; hsa-mir-652-3p ; hsa-mir-331-3p ; hsa-mir-222-3p ; hsa-mir-100-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-17-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-181b-3p ; hsa-mir-224-5p ; hsa-mir-130a-3p ; hsa-mir-181b-2-3p ; hsa-mir-106b-5p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-20b-5p ; hsa-mir-519c-3p ; hsa-mir-526b-3p ; hsa-mir-519b-3p ; hsa-mir-519d-3p ; hsa-mir-519a-3p ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-548t-5p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-4420 ; hsa-mir-5002-3p ; hsa-mir-548aw ; hsa-mir-548az-5p ; hsa-mir-141-3p ; hsa-mir-200a-3p ; hsa-mir-3607-3p ; hsa-mir-4668-3p ; hsa-mir-4722-3p ; hsa-mir-4769-3p ; hsa-mir-6727-3p ; hsa-mir-6817-5p ; hsa-mir-200b-3p ; hsa-mir-200c-3p ; hsa-mir-369-3p ; hsa-mir-429 ; hsa-mir-4282 ; hsa-mir-1277-5p ; hsa-mir-5011-5p ; hsa-mir-3161 ; hsa-mir-5689 ; hsa-mir-6776-3p ; hsa-mir-199a-3p ; hsa-mir-199b-3p ; hsa-mir-3129-5p ; hsa-mir-5582-5p ; hsa-mir-1468-3p ; hsa-mir-548f-5p ; hsa-mir-548g-5p ; hsa-mir-548x-5p ; hsa-mir-548aj-5p ; hsa-mir-6083 ; hsa-mir-302a-5p ; hsa-mir-8084 ; hsa-mir-1264 ; hsa-mir-455-5p ; hsa-mir-340-5p ; hsa-mir-6867-3p ; hsa-let-7d-3p ; hsa-mir-3684 ; hsa-mir-1909-5p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4469 ; hsa-mir-3692-3p ; hsa-mir-190a-3p ; hsa-mir-4801 ; hsa-mir-4731-3p ; hsa-mir-6747-3p ; hsa-mir-3910 ; hsa-mir-3714 ; hsa-mir-29a-3p ; hsa-mir-208a-3p ; hsa-mir-208b-3p ; hsa-mir-148a-3p

Nearest miRNA

hsa-mir-10398/Upstream/4728121; hsa-mir-1913/Downstream/3016480;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/76675, chr6-CpG: 64/Downstream/137579

Upstream sequence

TGAGTAAACGGATGCCTATATGGATGCTTCAGGGTGTGTAATATTATCAAGTGTTACAACAGCACATTGTTTAGAACGTTTAAGATTTAAGACGAGTAAG

Downstream sequence

TACTTTAAAAGGAGTCAAAAGAAGTGAAAGCAAATACTGAACCTCATCTTTTATAACATAAAAATGAATTTTTTCTTAATTATGAAAGCCTTTCACGTTT