Basic Information
VIS ID
TVIS44019687
Fusion event
HTLV-1-ZSCAN12P1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
28060074/28092296 (Hg38)
End
28060074/28092296 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
ZSCAN12P1
Nearest miRNA
hsa-mir-3143/Upstream/944608; hsa-mir-10398/Downstream/2492036;
Nearest TSS
ENST00000381078/Upstream/11166; ENST00000340487/Downstream/32264;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/198479, chr6-CpG: 43/Downstream/12390
Upstream sequence
CACCCGAATTGTTCATTTTCCTTTTGAATTGGTGGTTTGAATCAATGAATTTCAAGATAACTAGACGTCTTTAATCTTAAAAAAAAAAGTTCTTAGCAAC
Downstream sequence
CTTTTCATTTCTGCGAGTTAGTAATGATTTATTTTGCCTTAGGAGTGACCCAAAAGAAACTTGCTCAAGGACAGCCTCCTTAAAGCAGACTTCCATATAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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