Basic Information
VIS ID
TVIS44019688
Fusion event
HTLV-1-SERPINB9P1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p25.2
Reference genome
GRCh37/hg19
Start
2861815/2861581 (Hg38)
End
2861815/2861581 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
SERPINB9P1
Nearest miRNA
hsa-mir-4645/Upstream/7474; hsa-mir-10398/Downstream/2286652;
Nearest TSS
ENST00000381078/Upstream/19575; ENST00000437718/Downstream/14929;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/19542, chr6-CpG: 21/Downstream/13786
Upstream sequence
ccaccaggagtgaattaacaactccagatgcgttgccttaagaactgtaacattcactacgaaggtctgcagcttgcctcctgagccagcaagaccgtga
Downstream sequence
acccaccagaaaaaaaaaactccaaatacatctgaacatcaataaaggacagactccagatgtgccaccttaagtgctataacacatcatgagggtctgc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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