Basic Information
VIS ID
TVIS44019689
Fusion event
HTLV-1-LOC105375005 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
29284756/29316979 (Hg38)
End
29284756/29316979 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105375005
Nearest miRNA
hsa-mir-3143/Upstream/2169291; hsa-mir-10398/Downstream/1267353;
Nearest TSS
ENST00000381078/Upstream/10353; ENST00000623183/Downstream/39298;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/150783, chr6-CpG: 80/Downstream/236354
Nearby gene
OR14J1(+9324) ;
Upstream sequence
aaatgaaagaataagaaaggaaagggaaggaaTGCCAGCCTTTCCCTAAAGACACATGACACAACTTGAGACCAAAAGTCATAGCATTATAAACAGAATC
Downstream sequence
CCTACGTTTATAACTCTTTCTGTTTGATTTTTACCCTCAGAAGGAAGATTACAAAAAACAATGCAACTGAAATTCATACTTCATAATAATGGTTAAAGCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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