VISDB Viral Integration Site DataBase

VIS ID

TVIS44019710

Fusion event

HTLV-1-KLHDC3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr6

Cytoband

p21.1

Reference genome

Start

End

42988130/43020392 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-24-3p ; hsa-mir-877-3p ; hsa-mir-93-3p ; hsa-mir-20a-3p ; hsa-mir-324-5p ; hsa-mir-149-5p ; hsa-mir-3919 ; hsa-mir-4452 ; hsa-mir-4680-3p ; hsa-mir-3925-5p ; hsa-mir-6800-3p ; hsa-mir-3181 ; hsa-mir-30b-3p ; hsa-mir-6810-5p ; hsa-mir-432-3p ; hsa-mir-488-3p ; hsa-mir-3691-5p ; hsa-mir-3165 ; hsa-mir-4652-5p ; hsa-mir-3191-3p ; hsa-mir-3144-5p ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-4747-5p ; hsa-mir-5196-5p ; hsa-mir-6851-5p ; hsa-mir-1193 ; hsa-mir-3689d ; hsa-mir-6081 ; hsa-mir-6134 ; hsa-mir-5008-5p ; hsa-mir-3663-3p ; hsa-mir-3179 ; hsa-mir-6730-5p ; hsa-mir-5681a ; hsa-mir-4766-5p ; hsa-mir-6501-3p ; hsa-mir-6840-3p ; hsa-mir-6783-5p ; hsa-mir-6891-5p ; hsa-mir-646 ; hsa-mir-3173-3p ; hsa-mir-665 ; hsa-mir-29c-3p ; hsa-mir-29a-3p ; hsa-mir-29b-3p ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-513a-5p ; hsa-mir-4286 ; hsa-mir-181a-2-3p

Nearest miRNA

hsa-mir-10398/Upstream/1286782; hsa-mir-10524/Downstream/414150;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/6053, chr6-CpG: 39/Downstream/1048

Upstream sequence

GTGAGGCATTCCTGGTGAGGGTAAGGTGGAGGGGCTGCCTGGTTGGCTCTAAGCAAAGCAGGAAAGGCAGGTTGGGATGTTGACTGACATGTATACACAG

Downstream sequence

ATCTCAGGTGCCTGGACACTGCAATATACATACATACATAAACATAAACCGGAAATCCATATGAGCTTGGAGGTAGAGGAGTGGGTGGTGTTGGATTTGG