Basic Information
VIS ID
TVIS44019721
Fusion event
HTLV-1-TINAG integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
54249420/54384622 (Hg38)
End
54249420/54384622 (Hg38)
Orient
-
Location type
Intronic
Target gene
TINAG
Nearest miRNA
hsa-mir-10398/Upstream/1107551; hsa-mir-10524/Downstream/3005510;
Nearest TSS
ENST00000381078/Upstream/14651; ENST00000306858/Downstream/456233;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/588448, chr6-CpG: 74/Downstream/461733
Upstream sequence
caacaataaaaaaggaaagtagaagactgcaaaatgacattgctaaaatgctggataaaataataatattgataatgatgaagataacgtgccaacatgg
Downstream sequence
aattttatacatggtgacatttttctccaaaataaatacaaaattaaagcacgtttggacaaaagctgaaataacacaattccaaaaaaacatacaccaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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