Basic Information
VIS ID
TVIS44019730
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q12
Reference genome
GRCh37/hg19
Start
66440286/65730393 (Hg38)
End
66440286/65730393 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10398/Upstream/8340181; hsa-mir-10524/Downstream/5646567;
Nearest TSS
ENST00000381078/Upstream/23168; ENST00000449928/Downstream/2158946;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/428805, chr6-CpG: 34/Downstream/57389
Nearby gene
EYS(-23168) ;
Upstream sequence
AATAGGAGGGGGCACTCATGAGAAAGTCTCCAGTTTTACAATGTATTACATAGCAGATATTCAATAACCATTTAACAAGGAAACAAAAGTTATAGCATGT
Downstream sequence
AGAGTAGGCTACTTGGGGAAAGTTTTGATAAGAAGACGACATCTATAATGTGATCTACAGTATTTTAAAAGCATGCACAGAATGTTGTGCTAAGCAACAT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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