Basic Information
VIS ID
TVIS44019734
Fusion event
HTLV-1-ADGRB3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q13
Reference genome
GRCh37/hg19
Start
69979051/69269159 (Hg38)
End
69979051/69269159 (Hg38)
Orient
+
Location type
Intronic
Target gene
ADGRB3
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-10398/Upstream/11878947; hsa-mir-10524/Downstream/2107801;
Nearest TSS
ENST00000381078/Upstream/36125; ENST00000478620/Downstream/521506;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/634005, chr6-CpG: 53/Downstream/527241
Upstream sequence
tataaatcatcacatttacacctcaaaacaatgtaatacagttggttctttcatcctcccctttagaaacgcagaagctgaaacctacaaatgttaaata
Downstream sequence
tcttgcccaaggtcatataactagtacaagtcagaatcaagtattgaacttaggtttgtccaattccagaaacaacattcttAGTTAAAACAAAATACAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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