VISDB Viral Integration Site DataBase

VIS ID

TVIS44019742

Fusion event

HTLV-1-RREB1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr6

Cytoband

p24.3

Reference genome

Start

End

7252168/7251935 (Hg38)

Orient

+

Location type

UTR3

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-671-5p ; hsa-mir-106b-5p ; hsa-mir-30d-5p ; hsa-mir-145-5p ; hsa-mir-143-3p ; hsa-mir-889-3p ; hsa-mir-3653-3p ; hsa-mir-3658 ; hsa-mir-224-3p ; hsa-mir-137 ; hsa-mir-522-3p ; hsa-mir-4694-3p ; hsa-mir-4729 ; hsa-mir-485-3p ; hsa-mir-539-3p ; hsa-mir-582-5p ; hsa-mir-655-3p ; hsa-mir-374c-5p ; hsa-mir-5195-5p ; hsa-mir-545-5p ; hsa-mir-548t-3p ; hsa-mir-3150a-5p ; hsa-mir-3150b-5p ; hsa-mir-548aa ; hsa-mir-548ap-3p ; hsa-mir-548at-3p ; hsa-mir-548ay-3p ; hsa-mir-582-3p ; hsa-mir-548c-3p ; hsa-mir-4719 ; hsa-mir-218-5p ; hsa-mir-510-3p ; hsa-mir-431-5p ; hsa-mir-4764-5p ; hsa-mir-4738-3p ; hsa-mir-4635 ; hsa-mir-6507-5p ; hsa-mir-6782-5p ; hsa-mir-6803-5p ; hsa-mir-6751-5p ; hsa-mir-7109-5p ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-513a-5p ; hsa-mir-4472 ; hsa-mir-4447 ; hsa-mir-92a-2-5p ; hsa-mir-6766-5p ; hsa-mir-6756-5p ; hsa-mir-608 ; hsa-mir-7110-5p ; hsa-mir-4651 ; hsa-mir-6842-5p ; hsa-mir-6752-5p ; hsa-mir-6885-5p ; hsa-mir-328-5p ; hsa-mir-6887-5p ; hsa-mir-6795-5p ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-625-5p ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-3202 ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-27a-3p ; hsa-mir-3681-3p ; hsa-mir-128-3p ; hsa-mir-216a-3p ; hsa-mir-27b-3p ; hsa-mir-548g-3p ; hsa-mir-548av-3p ; hsa-mir-4684-5p ; hsa-mir-942-5p ; hsa-mir-599 ; hsa-mir-3143 ; hsa-mir-5087 ; hsa-mir-4720-3p ; hsa-mir-4804-3p ; hsa-mir-589-3p ; hsa-mir-410-3p ; hsa-mir-4773 ; hsa-mir-543 ; hsa-mir-101-3p ; hsa-mir-139-5p ; hsa-mir-3675-3p ; hsa-mir-144-3p ; hsa-mir-5692a ; hsa-mir-6801-5p ; hsa-mir-1178-5p ; hsa-mir-3912-3p ; hsa-mir-6873-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6818-3p ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-1304-3p ; hsa-mir-483-3p ; hsa-mir-421 ; hsa-mir-4709-5p ; hsa-mir-1976 ; hsa-mir-6893-3p ; hsa-mir-370-3p ; hsa-mir-450a-1-3p ; hsa-mir-4776-5p ; hsa-mir-6772-3p ; hsa-mir-4303 ; hsa-mir-3619-3p ; hsa-mir-4448 ; hsa-mir-4268 ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-591 ; hsa-mir-6751-3p ; hsa-mir-1199-5p ; hsa-mir-4653-5p ; hsa-mir-3921 ; hsa-mir-301b-5p ; hsa-mir-301a-5p ; hsa-mir-146a-3p ; hsa-mir-4254 ; hsa-mir-3690 ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-6892-3p ; hsa-mir-6865-3p

Nearest miRNA

hsa-mir-3691/Upstream/1082500; hsa-mir-10398/Downstream/3187782;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/4596, chr6-CpG: 21/Downstream/9150

Upstream sequence

CATGAACAGAGAATCACAAGTTTGGTTTTGGTACTTTTTGTTCCTCTTTGTATTCAGTTGTATAGAACTTCCAAATTCAGAATGAGAAGAAAGCTGTTCT

Downstream sequence

GTATCAAACCATTTAAGCAATAAATGTTATATTTTAAAAGCTGCAGATTGCCGGTCACGTGGCCGTCCTGTGATTTGTTGTGATCCCATCCCCAAACCCA