Basic Information
VIS ID
TVIS44019743
Fusion event
HTLV-1-LOC112267960 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q13
Reference genome
GRCh37/hg19
Start
73330375/72620647 (Hg38)
End
73330375/72620647 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA6D
Target gene
LOC112267960
Nearest miRNA
hsa-mir-10398/Upstream/1217026; hsa-mir-10524/Downstream/347040;
Nearest TSS
ENST00000381078/Upstream/253917; ENST00000443915/Downstream/1145;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/437473, chr6-CpG: 174/Downstream/567
Nearby gene
KCNQ5(+1196) ;
Upstream sequence
CAGAAGACAGAAATCAGCTGCCGCGGGCGTGGGTGTGTGTACAGGGTGGGGGAGAATTGGGAAAGTATTTATCTCGGAGGGGCGGAGACAGCTGCAAGAA
Downstream sequence
GACTTTTGTCTTAGCATTGTTTTAGCCTTAGGAAAGGAAAAGGCCCGAAGGAATCCACCTTGCAACTATCTGCTATGTCTTTGTGGTGGAAGCTTAGTTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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