Basic Information
VIS ID
TVIS44019790
Fusion event
HTLV-1-MGAM2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q34
Reference genome
GRCh37/hg19
Start
141830996/142131196 (Hg38)
End
141830996/142131196 (Hg38)
Orient
-
Location type
Intronic
Target gene
MGAM2
Nearest miRNA
hsa-mir-10399/Upstream/3087039; hsa-mir-11400/Downstream/343331;
Nearest TSS
ENST00000635602/Upstream/19442; ENST00000496337/Downstream/39974;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/392603, chr7-CpG: 68/Downstream/665683
Upstream sequence
TGGGAACAACTCCTTATGGCCCAGATACGTTAACTGCAAAATAAAATAAAAGCTAAAAGTCAGGcaggcgtggtggctcacgtctgtaatcccagcactt
Downstream sequence
cgagaggctgacgtgggtggatcatgaggtcaggagttcaagaccagcctgaccaatgtggtgaaaccccgtctctactaaaaatacaaaaattagctgg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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