Basic Information
VIS ID
TVIS44019811
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
19569792/19530169 (Hg38)
End
19569792/19530169 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1302-6/Upstream/1402860; hsa-mir-10399/Downstream/175189;
Nearest TSS
ENST00000635602/Upstream/176635; ENST00000590912/Downstream/170166;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/384759, chr7-CpG: 44/Downstream/178605
Nearby gene
TWISTNB(-165293) ;
Upstream sequence
ATGGAAGCTAGAAAATGTTTTGTAAAAATATATTTTCATAAAATGGCTTATAGAATATGGACCAAAGCTTCTGAAAAGTCTGATGTTTGAAATGGTGGGT
Downstream sequence
AAGTCAGCTGAGAGGAAGGCTGTGAAAGACCACAGCTGGTTGTTTTTTTGTTTGTTTATTTTTTTCAGAGTAATTTCACAACCCTTCCAAATTAGCATCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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