Basic Information
VIS ID
TVIS44019814
Fusion event
HTLV-1-LOC389473 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p15.3
Reference genome
GRCh37/hg19
Start
23521055/23481436 (Hg38)
End
23521055/23481436 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC389473
Nearest miRNA
hsa-mir-1183/Upstream/2010290; hsa-mir-10399/Downstream/2468483;
Nearest TSS
ENST00000635602/Upstream/10969; ENST00000484553/Downstream/24449;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/6643, chr7-CpG: 20/Downstream/9379
Nearby gene
RPS2P32(+8952) ;
Upstream sequence
CCTTTTTCTTCATTTAGATGTAACAAACCTAGTAGTTTATGTTTATCAATTGTCTGTATATCTCTATATTTTATCCATGTACTCTTGATGTATAGACATA
Downstream sequence
GTTTGAAACTCGTTTCCTTGTGGTAAGTGACCGAGATGCTGCCACAGGACCTGAGACACTGATGAATGGTGCTATTTTGGACTTTCATCATGCTCCTTGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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