Basic Information
VIS ID
TVIS44019822
Fusion event
HTLV-1-INMT-MINDY4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p14.3
Reference genome
GRCh37/hg19
Start
30900325/30860709 (Hg38)
End
30900325/30860709 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
INMT-MINDY4
Nearest miRNA
hsa-mir-1183/Upstream/570819; hsa-mir-10399/Downstream/1872272;
Nearest TSS
ENST00000635602/Upstream/2962; ENST00000482461/Downstream/50985;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/88775, chr7-CpG: 144/Downstream/191393
Upstream sequence
CAGCGCCCCCATCCATGCGGGGGCCCTCTGGCTCTGGGAGTCTAGGGCTCTGTGCTCGAGTGTGTCAGTTCTGGTGGTCACTGGGAGTGGGCGCCTTGTT
Downstream sequence
ACATGCATGCTCCTGCATGTAGCCCTGTCCCTCTGAAAGGGGCTTCAGGGTTCCATGCCCAGGCCAGTCTTCATGTTGTGCACAGCTGGGGGACTAGGGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate