Basic Information
VIS ID
TVIS44019839
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
42336103/42296504 (Hg38)
End
42336103/42296504 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1183/Upstream/5377072; hsa-mir-10399/Downstream/854391;
Nearest TSS
ENST00000635602/Upstream/58634; ENST00000432845/Downstream/409943;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/58649, chr7-CpG: 19/Downstream/196973
Nearby gene
GLI3(-59485) ;
Nearest cancer related gene
GLI3(OG, -59485) ;
Upstream sequence
gatgaggtttccccatgttgcccaggctggtctcgaactcctgacctcaagtgatttttctgctttggcctcccatggtgtgggattacaggtgtaaacA
Downstream sequence
Cctcagaaaaacattttaaatgtataatatgaaatacacatgattaaaaaggaagctaatgttgtcaaaatacagttgttaaaatatttttaaaagtcat
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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