Basic Information
VIS ID
TVIS44019860
Fusion event
HTLV-1-LINC01446 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
53776509/53708816 (Hg38)
End
53776509/53708816 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LINC01446
Nearest miRNA
hsa-mir-1183/Upstream/8827016; hsa-mir-10399/Downstream/3246969;
Nearest TSS
ENST00000635602/Upstream/140567; ENST00000629899/Downstream/103115;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/489317, chr7-CpG: 48/Downstream/833225
Upstream sequence
TCAGTAATTCTTTGATATCAAATAACATTGTAAGCTATTTGTCAGATGTGATGTAGTGTGGTGGAAATAACACACAACTGGGGACCTAGAATAATTCACT
Downstream sequence
CTAACCACAGCTCTATTGGGACCTATGTGATATCCGTGAAGTTGCCTTCGAGTGCAACCTCAAAATGTGGCTATAACTACAGTGTTCGTAAGTTACTATA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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