Basic Information
VIS ID
TVIS44019886
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q11.23
Reference genome
GRCh37/hg19
Start
73850942/74436612 (Hg38)
End
73850942/74436612 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA7J
Nearest miRNA
hsa-mir-1183/Upstream/245318; hsa-mir-10399/Downstream/159356;
Nearest TSS
ENST00000635602/Upstream/36130; ENST00000489094/Downstream/17178;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/60432, chr7-CpG: 95/Downstream/16845
Nearby gene
GTF2IRD1(+17178) ;
Upstream sequence
attgaaatcatagcattctgctcctgggcccccaaaactcatgtccttttcacgttcacatatgacatacattcattccagccaggcacaatggctcacg
Downstream sequence
tctgtaatcccagcactttgggaggccaaggtgggaggatcacctaagcccaggaagtcgaggctgcagtgagccacaattgcgccactgcactttaacc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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