VISDB Viral Integration Site DataBase

VIS ID

TVIS44019907

Fusion event

HTLV-1-TECPR1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr7

Cytoband

q21.3

Reference genome

Start

End

97879405/98250093 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-8057 ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-760 ; hsa-mir-6822-3p ; hsa-mir-7114-3p ; hsa-mir-1180-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-7853-5p ; hsa-mir-105-5p ; hsa-mir-5698 ; hsa-mir-7156-3p ; hsa-mir-7641 ; hsa-mir-143-5p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-4284 ; hsa-mir-3622b-5p ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-6499-3p ; hsa-mir-4695-3p ; hsa-mir-1184 ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-1304-3p ; hsa-mir-6741-3p ; hsa-mir-4485-5p ; hsa-mir-5693 ; hsa-mir-6890-3p ; hsa-mir-509-5p ; hsa-mir-509-3-5p ; hsa-mir-4418 ; hsa-mir-1273f ; hsa-mir-1289 ; hsa-mir-129-5p ; hsa-mir-143-3p ; hsa-mir-3198 ; hsa-mir-4294 ; hsa-mir-4309 ; hsa-mir-4534 ; hsa-mir-4708-5p ; hsa-mir-4770 ; hsa-mir-593-3p ; hsa-mir-6088 ; hsa-mir-6514-5p ; hsa-mir-8055 ; hsa-mir-8082

Nearest miRNA

hsa-mir-10525/Upstream/285612; hsa-mir-10399/Downstream/631557;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/37400, chr7-CpG: 81/Downstream/1727

Upstream sequence

CTCTGCACACAGTGGGTGTTGAAACAACATTTAAGGATAATCACCACCACCTACCTCCAACACACTGCCAACTCCCTGATCTAAGACAGAAATACTTCTC

Downstream sequence

CAGGGAAAACAAATGCCACAAATAACTTGAAAAGTAAGGTCATAattggtggacagatatgtgataaagcaagtaaagtgtcaatagtagaatctagttg