Basic Information
VIS ID
TVIS44019913
Fusion event
HTLV-1-chr8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
104472067/103459839 (Hg38)
End
104472067/103459839 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA8A
Nearest miRNA
hsa-mir-12123/Upstream/305150; hsa-mir-10400/Downstream/1024530;
Nearest TSS
ENST00000518652/Upstream/20357; ENST00000562917/Downstream/4550;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/44244, chr8-CpG: 243/Downstream/38988
Nearby gene
DCAF13(+16387) ;
Upstream sequence
GCCTTAATGAATTACTACACTCTTAATGAATTACTACACTCTTAATGAATTACTACACTCTTCTTCCAGTATCTCTACTCCCTGGCTCTAGTCCATGCCC
Downstream sequence
TATAATAAGACCTTCTTATCTCAATCAGGTGCTCAGTTGTAATGTAATTGTTGTTGCTAACCAGGTTTTGGTTGGTTAAAACTTGTGATTCAAAAAGATA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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