Basic Information
VIS ID
TVIS44019915
Fusion event
HTLV-1-ANGPT1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
108457767/107445539 (Hg38)
End
108457767/107445539 (Hg38)
Orient
-
Location type
Intronic
Target gene
ANGPT1
Nearest miRNA
hsa-mir-12123/Upstream/2961074; hsa-mir-10400/Downstream/5197954;
Nearest TSS
ENST00000518652/Upstream/109017; ENST00000520037/Downstream/49456;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/787176, chr8-CpG: 92/Downstream/637088
Upstream sequence
CAAAAATTATATGTGGTCAGTGGTCAGCTAAAATTGGATGACTTTGGCCAAGTATTTAGGTTTCTTAAATATATATTATGGACCTCCTACTTTTTTTTTC
Downstream sequence
CAAATTCTATTTTACATTGTAGGCAATCTGTTCACACATCAGTGTCTGAGGAGAGACATCAATCAGAAATCCAAGAACTtccaattaacttttatcgggc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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