Basic Information
VIS ID
TVIS44019920
Fusion event
HTLV-1-chr8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
117385807/116373569 (Hg38)
End
117385807/116373569 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-12123/Upstream/3729986; hsa-mir-10400/Downstream/501159;
Nearest TSS
ENST00000518652/Upstream/48510; ENST00000519443/Downstream/30188;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/704173, chr8-CpG: 21/Downstream/382122
Nearby gene
LINC00536(No orient, 48510)
Upstream sequence
ctgacttctgtgcacccgcaggatcaacaccccatggaagcttccaaggattggggcttgcactctctgaagccacagcctgagctgtaccttggcctct
Downstream sequence
tttagccatagctagagcagctgagccacaatgcaccaagtccctaagctgcacacagcagagggccctgtactcacaaagccatttttttcctcctagg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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