Basic Information
VIS ID
TVIS44019923
Fusion event
HTLV-1-LOC105375721 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.11
Reference genome
GRCh37/hg19
Start
118649897/117637658 (Hg38)
End
118649897/117637658 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105375721
Nearest miRNA
hsa-mir-12123/Upstream/762858; hsa-mir-10400/Downstream/1687513;
Nearest TSS
ENST00000518652/Upstream/107294; ENST00000366457/Downstream/472756;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/116586, chr8-CpG: 76/Downstream/474077
Nearby gene
MED30(+97396) ;
Upstream sequence
tctggccagggcaatcaggcaggagaaggaaataaagggtattcaattaggaaaagaggaagacaaattgtccctgtttgcagatgacatgattgtgtat
Downstream sequence
atctagaaaaccccatcgtctcagcccaaaatctccttaaggtgataagcaacttcagcTTtgggtatttataatacccaaaggattataaatcatgctg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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