Basic Information
VIS ID
TVIS44019930
Fusion event
HTLV-1-chr8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.13
Reference genome
GRCh37/hg19
Start
125929650/124917408 (Hg38)
End
125929650/124917408 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA8C ; FRA8E
Nearest miRNA
hsa-mir-12123/Upstream/95350; hsa-mir-10400/Downstream/2878554;
Nearest TSS
ENST00000518652/Upstream/59892; ENST00000533286/Downstream/22941;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/188383, chr8-CpG: 103/Downstream/80647
Nearby gene
LINC00964(No orient, 24600)
Upstream sequence
tttttgtatttttagtagagacagggtttcaccatgttggccaggctgctctcgaactcctgacttcgtgatccgcccgcctcaacctcccaaagtgctg
Downstream sequence
agattacaggtgtgagccaccacaccaggccAGGCACAAGCTTTTAACAAGACACTTGAAAACTTTTTCTCTAATTCTTCTATATCATCCCTTCACTGAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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