Basic Information
VIS ID
TVIS44019934
Fusion event
HTLV-1-ADCY8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.22
Reference genome
GRCh37/hg19
Start
131995484/130983238 (Hg38)
End
131995484/130983238 (Hg38)
Orient
-
Location type
Intronic
Target gene
ADCY8
Nearest miRNA
hsa-mir-1204/Upstream/974785; hsa-mir-10400/Downstream/2063243;
Nearest TSS
ENST00000518652/Upstream/47829; ENST00000519005/Downstream/7627;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/539199, chr8-CpG: 207/Downstream/56765
Upstream sequence
ATTAAGGTACTCAACAATGGATGGTAAAGCACCCCAAGGTTAGGAAGGGCAGGCAGCTACAAACACCCATGGAATCTGGCAAATCCTTTActctaagcga
Downstream sequence
gggctgcctaataggaactgtggcttttggtagataaatgcagccactgtaaatctacaatccagcagggtaggatatgggaagataaatgtatggacgt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate