Basic Information
VIS ID
TVIS44019947
Fusion event
HTLV-1-chr8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
144507370/143425200 (Hg38)
End
144507370/143425200 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA8D
Nearest miRNA
hsa-mir-1204/Upstream/1248782; hsa-mir-10400/Downstream/307883;
Nearest TSS
ENST00000518652/Upstream/7521; ENST00000517300/Downstream/4698;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/3562, chr8-CpG: 299/Downstream/3480
Nearby gene
MAFA(-2860) ;
Nearest cancer related gene
MAFA(OG, -2860) ;
Upstream sequence
TGCGTGGCTGACGGGGGCTTAAGGCAGGAGACCAGTGACCATCCAGGTGGGCTGTCGGGCCCAGGCGAGCGTGTGTGTGGGGGGTACAGATGGGCTGTCG
Downstream sequence
GGCACGGGCGAGTGTGCGCGTGGGGGGGTCCAGGTGGGCTGTCGGGCACAGACGTGTGTGTGCGTGGGGTCCAGGTGGGCTGCGGGCACAGACGTGTGTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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