Basic Information
VIS ID
TVIS44020008
Fusion event
HTLV-1-chr8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
57057188/56144629 (Hg38)
End
57057188/56144629 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/13248354; hsa-mir-10400/Downstream/5570159;
Nearest TSS
ENST00000518652/Upstream/30647; ENST00000518169/Downstream/26795;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/26304, chr8-CpG: 44/Downstream/12499
Nearby gene
PLAG1(-16280) ;
Nearest cancer related gene
PLAG1(OG, -16280) ;
Upstream sequence
gtcttgtactttactttccccactcctagaagcagccctgaatgttttagtggagaatggtacttggaaaccaagatttgggtatttagtgtgctcatta
Downstream sequence
ctactagctatcactgcttctaagcctgctcagatggcagagttaggaaatacatatatgcatgcttgtgtgtgtgtatatatacatatatctctatgtc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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