Basic Information
VIS ID
TVIS44020027
Fusion event
HTLV-1-XKR5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p23.1
Reference genome
GRCh37/hg19
Start
6691904/6834382 (Hg38)
End
6691904/6834382 (Hg38)
Orient
+
Location type
Intronic
Target gene
XKR5
Nearest miRNA
hsa-mir-3674/Upstream/89138; hsa-mir-10400/Downstream/1254559;
Nearest TSS
ENST00000518652/Upstream/86698; ENST00000500823/Downstream/1116;
Nearest CpG islands
chr8-CpG: 118/Target, None/Upstream, None/Downstream
Upstream sequence
GGAAAACTGCCCTGAGGTACAGCTGCAGACGCTGCAGCTCTAGACCGCGGGGTCCGGGCTCAGGCAGCCCTTAGCGCCCAGGCTGGGTCCGGCTGTCACC
Downstream sequence
ACCCCGAGCGTCCTGCGGCAGCCTCCCTTGCACGAAAAGCCTTCGGTGCTGCAGGGCTGGGGAATGCTGACACCCAGTCCGTGCCCAGCTGGAGGGCAAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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