VISDB Viral Integration Site DataBase

VIS ID

TVIS44020036

Fusion event

HTLV-1-ZNF704 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr8

Cytoband

q21.13

Reference genome

Start

End

81597693/80685458 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-192-5p ; hsa-mir-744-5p ; hsa-mir-511-5p ; hsa-mir-23c ; hsa-mir-23b-3p ; hsa-mir-23a-3p ; hsa-mir-130a-5p ; hsa-mir-431-5p ; hsa-mir-4635 ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-203a-3p ; hsa-mir-4423-3p ; hsa-mir-6069 ; hsa-mir-4745-3p ; hsa-mir-1538 ; hsa-mir-3934-3p ; hsa-mir-484 ; hsa-mir-3155b ; hsa-mir-3155a ; hsa-mir-3622a-5p ; hsa-mir-5582-5p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-152-5p ; hsa-mir-597-3p ; hsa-mir-182-3p ; hsa-mir-4267 ; hsa-mir-203b-3p ; hsa-mir-7158-3p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-3663-5p ; hsa-mir-6513-3p ; hsa-mir-888-3p ; hsa-mir-606 ; hsa-mir-6826-3p ; hsa-mir-6892-3p ; hsa-mir-6795-3p ; hsa-mir-6887-3p ; hsa-mir-135a-3p ; hsa-mir-3158-3p ; hsa-mir-4446-3p ; hsa-mir-5088-5p ; hsa-mir-643 ; hsa-mir-4446-5p ; hsa-mir-3679-3p ; hsa-mir-675-3p ; hsa-mir-2355-5p ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-621 ; hsa-mir-1468-3p ; hsa-mir-6793-3p ; hsa-mir-545-3p ; hsa-mir-3146 ; hsa-mir-646 ; hsa-mir-503-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-548p ; hsa-let-7a-2-3p ; hsa-let-7g-3p ; hsa-mir-130b-5p ; hsa-mir-133a-3p ; hsa-mir-133b ; hsa-mir-3120-5p ; hsa-mir-3177-5p ; hsa-mir-4421 ; hsa-mir-4527 ; hsa-mir-4753-3p ; hsa-mir-5699-3p ; hsa-mir-6503-5p ; hsa-mir-6753-3p ; hsa-mir-6809-3p ; hsa-mir-6843-3p ; hsa-mir-6848-3p ; hsa-mir-7107-3p ; hsa-mir-942-5p ; hsa-mir-9-5p

Nearest miRNA

hsa-mir-12123/Upstream/443985; hsa-mir-10400/Downstream/10520027;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/106357, chr8-CpG: 181/Downstream/187732

Upstream sequence

GGGGTTCCCTGTACTGTGAGTCCTTGTCACAACCCTGGGCCGTGAGTCCTTGTCACAACCCTGGGCCATGCCTATTGAGTGTTCGAACTACACACTCAGA

Downstream sequence

AAACCCCAGGGAGACAGTCTGTGAAGCTCAAAGTAACAGGAAAAGACTTCAGGTCCCTACCACTGTCCTGCCTGCAGGTACCCACTGATACAAGTGCCAG