Basic Information
VIS ID
TVIS44020066
Fusion event
HTLV-1-LOC105376197 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
107876024/105113743 (Hg38)
End
107876024/105113743 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105376197
Nearest miRNA
hsa-let-7a-1/Upstream/6884526; hsa-mir-12126/Downstream/1487185;
Nearest TSS
ENST00000422679/Upstream/121962; ENST00000607692/Downstream/130879;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/145157, chr9-CpG: 137/Downstream/130443
Nearby gene
SLC44A1(+130870) ;
Upstream sequence
tgggaggtggaggttgcagtgagccgaaatcaggccagtgcactccagcctgcgtgacagcgagacaatgtctcaaaaaaaaaaaaaaaaaaGGTAATAA
Downstream sequence
TAGAGTTTTAATATTGGAGACAGAATAAATCAATAAAAATAATCCCAACCATTAATCTTTAGTTTAGCCTATTAGTTTCAAACTTTCTTCCACACCAAAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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