VISDB Viral Integration Site DataBase

VIS ID

TVIS44020071

Fusion event

HTLV-1-PALM2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr9

Cytoband

q31.3

Reference genome

Start

End

112410695/109648415 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-149-5p ; hsa-mir-340-5p ; hsa-mir-4667-3p ; hsa-mir-6887-3p ; hsa-mir-3163 ; hsa-mir-5582-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-3915 ; hsa-mir-6895-3p ; hsa-mir-4710 ; hsa-mir-3148 ; hsa-mir-3928-3p ; hsa-mir-4518 ; hsa-mir-1266-5p ; hsa-mir-3664-3p ; hsa-mir-764 ; hsa-mir-3934-5p ; hsa-mir-125a-3p ; hsa-mir-4433b-5p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-532-3p ; hsa-mir-1224-3p ; hsa-mir-609 ; hsa-mir-4264 ; hsa-mir-4704-3p ; hsa-mir-7705 ; hsa-mir-6854-5p ; hsa-mir-6885-3p ; hsa-mir-6881-3p ; hsa-mir-5089-3p ; hsa-mir-642a-5p ; hsa-mir-642b-5p ; hsa-mir-591 ; hsa-mir-4469 ; hsa-mir-5193 ; hsa-mir-877-3p ; hsa-mir-1470 ; hsa-mir-4716-5p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4753-3p ; hsa-mir-4448 ; hsa-mir-302d-5p ; hsa-mir-302b-5p ; hsa-mir-4778-3p ; hsa-mir-1236-3p ; hsa-mir-6515-3p ; hsa-mir-1915-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-4279 ; hsa-mir-4722-3p ; hsa-mir-4726-3p ; hsa-mir-4740-3p ; hsa-mir-498 ; hsa-mir-622 ; hsa-mir-6727-3p ; hsa-mir-6747-3p ; hsa-mir-6764-5p ; hsa-mir-6778-3p ; hsa-mir-6791-3p ; hsa-mir-6829-3p ; hsa-mir-6836-3p ; hsa-mir-6840-3p

Nearest miRNA

hsa-let-7a-1/Upstream/136870; hsa-mir-12126/Downstream/1622741;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/7346, chr9-CpG: 56/Downstream/131618

Upstream sequence

TCAAAGTTTTTAGCATTTGCAAATTTGAACATAATTCTCTTAattcattcaatcgacggattctttttgagtgcccttttcatcctaggcactgctccaa

Downstream sequence

gcactgagaatacagcagtaaattgtcaaagaggcaaaggagcttatattgtgttagaggagacagacaatacatatattacatatatactttgtcagga