Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene131858830131860107132079908131964880131972970131958440131962344131942035131945715131916042131919465131935813131938815131929051131930573131946229131946604131951974131952143131969369
Basic Information
VIS ID
TVIS44020091
Fusion event
HTLV-1-MED27 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q34.13
Reference genome
GRCh37/hg19
Start
134844756/131969369 (Hg38)
End
134844756/131969369 (Hg38)
Orient
+
Location type
Intronic
Target gene
MED27
Nearest miRNA
hsa-let-7a-1/Upstream/1343006; hsa-mir-126/Downstream/976338;
Nearest TSS
ENST00000422679/Upstream/153177; ENST00000372179/Downstream/110276;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/127162, chr9-CpG: 33/Downstream/110204
Upstream sequence
TACTCAGTCTTAGATATCAGGGACTCCATAAAGGAAAGACAGAAACCAAGATATCAGTCCTCTTTGCTGGGACAGGGTGAGCCTGGATTTTTAGTTTTTG
Downstream sequence
GTGACGGTTGATTCAGTGTATATTTCATTACTATTTTAAACATCTTCAATGGAGGTTTCTTCTTGCATTTTGTACATTAAGTGCTCTCGTAACATTTTAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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