Basic Information
VIS ID
TVIS44020093
Fusion event
HTLV-1-FAM163B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q34.2
Reference genome
GRCh37/hg19
Start
136448955/133583833 (Hg38)
End
136448955/133583833 (Hg38)
Orient
+
Location type
Intronic
Target gene
FAM163B
Nearest miRNA
hsa-let-7a-1/Upstream/531774; hsa-mir-126/Downstream/795578;
Nearest TSS
ENST00000422679/Upstream/3587; ENST00000263611/Downstream/2364;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/4351, chr9-CpG: 19/Downstream/2057
Nearby gene
FAM163B(-3587) ;
Upstream sequence
AAGGGTGCCGGCTCAGGCCAGGTGCCCAGGGCTGTCAGCAGCCACCCTCCAACACCCAGGCTGGTCCAGCTGGAGCCTCTCAGCCTCGCTCTGCAGATAC
Downstream sequence
ACGCCTGCCGAGGAGCAGCAACGCCCGAGACGGCGCCAGGTCCCAGGGCCAGGCATGGCCGACAGACACACACTCCGCTGGCAGCTCCACCAGCGCCCAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate