VISDB Viral Integration Site DataBase

VIS ID

TVIS44020106

Fusion event

HTLV-1-BNC2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr9

Cytoband

p22.3

Reference genome

Start

End

16585027/16585029 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-16-5p ; hsa-mir-629-3p ; hsa-mir-3973 ; hsa-mir-6510-5p ; hsa-mir-3175 ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-574-5p ; hsa-mir-6867-5p ; hsa-mir-8064 ; hsa-mir-892a ; hsa-mir-297 ; hsa-mir-4666b ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-455-5p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-4439 ; hsa-mir-3136-5p ; hsa-mir-873-3p ; hsa-mir-6857-3p ; hsa-mir-6855-3p ; hsa-mir-4513 ; hsa-mir-4499 ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-2278 ; hsa-mir-561-3p ; hsa-mir-7152-5p ; hsa-mir-3074-5p ; hsa-mir-17-3p ; hsa-mir-545-5p ; hsa-mir-410-3p ; hsa-mir-6867-3p ; hsa-mir-516a-5p ; hsa-mir-4713-5p ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-6740-3p ; hsa-mir-942-5p ; hsa-mir-1264 ; hsa-mir-510-3p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4315 ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-3691-3p ; hsa-mir-3908 ; hsa-mir-568

Nearest miRNA

hsa-mir-101-2/Upstream/10577125; hsa-let-7a-1/Downstream/1988277;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/1031693, chr9-CpG: 30/Downstream/141832

Upstream sequence

AATTTGAAGTGCAATAATAAAAGCTTTCATAAATGCTTTAAAAAAAATAGCTCTGCTTTACCGAAATCAAGGGAGGGCCAATAAAATGAGATGGTATTTC

Downstream sequence

AAGGACAGTTAATATAAACTCCAGCACAAAAGACACaaatatttaaatcattaatttgataatatttaattattttataaaaatatCCTAATTTTGTATT