VISDB Viral Integration Site DataBase

VIS ID

TVIS44020112

Fusion event

HTLV-1-ACER2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr9

Cytoband

p22.1

Reference genome

Start

End

19448959/19448961 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-let-7a-5p ; hsa-let-7b-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-mir-98-5p ; hsa-mir-196a-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-196b-5p ; hsa-mir-541-5p ; hsa-mir-4257 ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-mir-122-5p ; hsa-mir-329-5p ; hsa-mir-504-3p ; hsa-mir-4280 ; hsa-mir-4464 ; hsa-mir-4748 ; hsa-mir-498 ; hsa-mir-505-3p ; hsa-mir-548v ; hsa-mir-4700-3p ; hsa-mir-513b-3p ; hsa-mir-7150 ; hsa-mir-4512 ; hsa-mir-106b-5p ; hsa-mir-20a-5p ; hsa-mir-20b-5p ; hsa-mir-106a-5p ; hsa-mir-17-5p ; hsa-mir-519d-3p ; hsa-mir-526b-3p ; hsa-mir-93-5p ; hsa-mir-182-5p ; hsa-mir-96-5p ; hsa-mir-1271-5p ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-140-3p ; hsa-mir-1244 ; hsa-mir-3613-3p ; hsa-mir-27a-5p ; hsa-mir-4668-5p ; hsa-mir-199a-3p ; hsa-mir-199b-3p ; hsa-mir-215-3p ; hsa-mir-222-5p ; hsa-mir-3120-5p ; hsa-mir-3129-5p ; hsa-mir-5007-5p ; hsa-mir-6753-3p ; hsa-mir-6773-3p ; hsa-mir-6777-3p ; hsa-mir-6888-3p ; hsa-mir-7107-3p ; hsa-mir-936

Nearest miRNA

hsa-mir-101-2/Upstream/875582; hsa-let-7a-1/Downstream/962187;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/39674, chr9-CpG: 91/Downstream/339256

Upstream sequence

cgggcgtggtggctcacgcccgtaatctcagcactttgggaggccgaggcaggtggatcaccaggtcaggagatcgagaccatcctggctaacacggtga

Downstream sequence

aaccccgtctctactaaaaatgcaaaaaattagccggatgtgcatgtagtcccagctatttgggaggttgaggcaggagaatcgtttgaacctgggaggc