VISDB Viral Integration Site DataBase

VIS ID

TVIS44020129

Fusion event

HTLV-1-TLN1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr9

Cytoband

p13.3

Reference genome

Start

End

35698016/35698019 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-760 ; hsa-mir-92b-3p ; hsa-mir-484 ; hsa-mir-186-5p ; hsa-mir-222-3p ; hsa-mir-92a-3p ; hsa-mir-25-3p ; hsa-let-7b-5p ; hsa-mir-218-5p ; hsa-mir-2681-5p ; hsa-mir-3682-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-6827-3p ; hsa-mir-340-3p ; hsa-mir-3613-3p ; hsa-mir-4282 ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-7977 ; hsa-mir-920 ; hsa-mir-6726-5p ; hsa-mir-5591-5p ; hsa-mir-4300 ; hsa-mir-6090 ; hsa-mir-6827-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-544b ; hsa-mir-383-3p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-4293 ; hsa-mir-6821-5p ; hsa-mir-1268b ; hsa-mir-1268a ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-561-5p ; hsa-mir-6830-5p ; hsa-mir-8080 ; hsa-mir-193b-3p ; hsa-mir-193a-3p ; hsa-mir-1229-5p ; hsa-mir-1275 ; hsa-mir-197-5p ; hsa-mir-3115 ; hsa-mir-3132 ; hsa-mir-4271 ; hsa-mir-4447 ; hsa-mir-4472 ; hsa-mir-4525 ; hsa-mir-4651 ; hsa-mir-4662a-3p ; hsa-mir-4665-5p ; hsa-mir-4723-5p ; hsa-mir-4725-3p ; hsa-mir-4731-5p ; hsa-mir-5010-5p ; hsa-mir-5698 ; hsa-mir-608 ; hsa-mir-625-5p ; hsa-mir-637 ; hsa-mir-6751-5p ; hsa-mir-6752-5p ; hsa-mir-6756-5p ; hsa-mir-6766-5p ; hsa-mir-6769a-3p ; hsa-mir-6780b-5p ; hsa-mir-6782-5p ; hsa-mir-6803-5p ; hsa-mir-6835-5p ; hsa-mir-6842-5p ; hsa-mir-6870-5p ; hsa-mir-7110-5p ; hsa-mir-7111-5p ; hsa-mir-92a-2-5p

Nearest miRNA

hsa-mir-101-2/Upstream/89860; hsa-let-7a-1/Downstream/12657;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/7287, chr9-CpG: 89/Downstream/33794

Upstream sequence

AGGGTGGAGATCGGGGACTTAGTTCAGTGAGGATGCACAGCAGGGGCATAGGGTAGTTGGGACCAGCGCAGGCAACATGACTGCCCTCCTGACAGCGTCC

Downstream sequence

CTCAGCATCTGGGGTGAAGCTCACCTGGGCAATGCCGCCAACCATCTTCTCTTTCACCACCACTGTCTCATTCTCCTGCTCTTCAAAGGCTGCAGCCTTC