VISDB Viral Integration Site DataBase

VIS ID

TVIS44020131

Fusion event

HTLV-1-MELK integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr9

Cytoband

p13.2

Reference genome

Start

End

36575895/36575898 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-193b-3p ; hsa-mir-4668-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-7703 ; hsa-mir-3115 ; hsa-mir-4252 ; hsa-mir-5186 ; hsa-mir-4793-3p ; hsa-mir-3925-3p ; hsa-mir-770-5p ; hsa-mir-4712-5p ; hsa-mir-1273g-3p ; hsa-mir-508-5p ; hsa-mir-4284 ; hsa-mir-891b ; hsa-mir-4772-3p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-4330 ; hsa-mir-1304-3p ; hsa-mir-6741-3p ; hsa-mir-10b-3p ; hsa-mir-6890-3p ; hsa-mir-6800-3p ; hsa-mir-640 ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-7107-5p ; hsa-mir-1234-3p ; hsa-mir-1224-3p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-3973 ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-6736-5p ; hsa-mir-4701-3p ; hsa-mir-1262 ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-378a-5p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-3653-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4683 ; hsa-mir-4768-3p ; hsa-mir-4786-5p ; hsa-mir-6502-3p ; hsa-mir-6888-5p

Nearest miRNA

hsa-mir-101-2/Upstream/842903; hsa-let-7a-1/Downstream/247641;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/87812, chr9-CpG: 29/Downstream/163639

Upstream sequence

CTTTCTGAGTGACAATTTGAAATAGCCCAGTCCTTTGCATGGAATGTAAACATGTGCATTCAGATTTATAGTCCAGTGTTCCTCCATTTCCATTCTCCTG

Downstream sequence

CTCTCTTTTTTCTTCTGTATCAGGATTCCAAAGATTTCTGAGCCTTAGGTTGACCTCTATACTTTTACTGTTTTTATTGCCTTTTGGAATTTCTTAGTCC