Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene6825919368328308685310616839388168406500683551896835785268366401683676006835637668357201683576006835800068395127
Basic Information
VIS ID
TVIS44020147
Fusion event
HTLV-1-PGM5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q21.11
Reference genome
GRCh37/hg19
Start
71010043/68395127 (Hg38)
End
71010043/68395127 (Hg38)
Orient
-
Location type
Intronic
Target gene
PGM5
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-124-3p
Nearest miRNA
hsa-mir-101-2/Upstream/27161292; hsa-let-7a-1/Downstream/2414848;
Nearest TSS
ENST00000422679/Upstream/37275; ENST00000587852/Downstream/1397;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/37439, chr9-CpG: 122/Downstream/309655
Upstream sequence
gtctttgtcaactacaagaaatttttgcttcctccaaggtcagagagatattttctccatattttcttctagagtcattgcagtttcaacttttacactt
Downstream sequence
atgtctagaatgattttgaattaatttttgagcacggtataaggtaggggtcgaggttcacttatttcccttatccagtttttccaatcccatttttaaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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